Reuben S. Harris

Biochemistry, Molecular Biology and Biophysics
Medical School and College of Biological Sciences
Twin Cities

Award Year
University Award
Distinguished McKnight University Professors
Research Title
Mechanisms of Mutation in Immunity and Cancer

Section A, Location 14

Reuben Harris is dedicated to advancing frontiers in mutation research. He has made breakthrough discoveries on mechanisms of mutation in multiple areas including bacterial evolution, antibody diversification, retrovirus restriction, and cancer pathogenesis. His fundamental discoveries have become textbook models and informed strategies for improving human health. His recent work on cancer mutation has revealed a major pathogenic role for enzymes called APOBECs, and this breakthrough has created clear opportunities for diagnostic and therapeutic advances.