Pediatrics
Medical School
Twin Cities
Award Year
2020
University Award
McKnight Land-Grant Professorship
Research Title
Novel Therapies for Cancer and Genetic Disorders using Genome Engineered Immune Cells
No Monument Location
Recent technological advances afford the ability to change the DNA, or genetic code, of human cells with unprecedented efficiency and fidelity, termed ‘genome engineering’. In parallel, the use of immune cells to treat cancer and disease has demonstrated great therapeutic promise, an approach termed ‘cancer immunotherapy’. However, immunotherapy has demonstrated limited success against advanced cancers. By implementing genome engineering in immune cells, it is now possible to develop immunotherapies capable of curing advanced cancer cases.