Members are elected for their achievement in medicine and health (see the National Academy of Medicine web site for details and history about this award). The University has had 16 members named since the Institute of Medicine's establishment in 1970.
| Member | Department | Date |
| Harry T. Orr | Laboratory Medicine & Pathology | 2014 |
| Bruce Blazar | Pediatrics | 2012 |
| Mary Story | Epidemiology | 2010 |
| Karen Hsiao Ashe | Neurology | 2009 |
| Michelle Biros | Emergency Medicine | 2009 |
| Selwyn M. Vickers | Surgery | 2009 |
| Susan M. Wolf | Law, Medicine & Bioethics | 2009 |
| Kamil Ugurbil | Radiology, Neurosciences & Medicine | 2007 |
| Michael Osterholm | Epidemiology | 2004 |
| Apostolos Georgeopoulos | Neuroscience | 2004 |
| Ashley T. Haase | Microbiology | 2003 |
| Deborah E. Powell | Medicine | 2000 |
| Robert J. Gorlin | Oral Sciences | 1997 |
| Paul G. Quie | Pediatrics | 1986 |
| Norman Garmezy | Psychology | 1986 |
| Robert A. Good | Pediatrics & Microbiology | 1970 |